Is functional cure achievable in children perinatally exposed to HIV?
نویسندگان
چکیده
Background A successful therapeutic course in children infected with HIV relies heavily on their adherence to antiretroviral treatment (ART). The adherence is influenced by every child’s particularities, his family or caregivers and, last but not least, by the selected therapeutic regimen. In newborns and toddlers, who depend completely on their family or caregivers, issues affecting adherence are essential.
منابع مشابه
Key Facts about Epidemiology of HIV/AIDS in Children Worldwide
Unfortunately, we do not know how many perinatally (Human Immunodeficiency Virus) HIV-infected pepole are living in contries today, while knowing these informations is necessary. UNAIDS reports that there are 3.4 million children under 15 years of age with HIV and 2 million adolescents between 10 and 19 years of age. Although the vast majority of children were perinatally infected, older childr...
متن کاملImmunizations in children exposed perinatally to HIV – from theory to practice
Increased vulnerability of HIV infected children to numerous infections argues vaccination to protect them. Lately we faced diseases preventable by vaccination in children perinatally exposed to HIV infection and, prematurity, abandonment, social condition, lack of understanding, drug mothers are among the causes that prevent children from immunization HIV-positive women. During 01.01.2011-31.1...
متن کاملNatural killer cells in perinatally HIV-1-infected children exhibit less degranulation compared to HIV-1-exposed uninfected children and their expression of KIR2DL3, NKG2C, and NKp46 correlates with disease severity.
NK cells play an integral role in the innate immune response by targeting virally infected and transformed cells with direct killing and providing help to adaptive responses through cytokine secretion. Whereas recent studies have focused on NK cells in HIV-1-infected adults, the role of NK cells in perinatally HIV-1-infected children is less studied. Using multiparametric flow cytometric analys...
متن کاملPredictors of change in the functional status of children with human immunodeficiency virus infection.
OBJECTIVE The purpose of this study was to identify important clinical predictors of change in the functional status of children with perinatally acquired human immunodeficiency virus (HIV) infection. METHODS Children who were perinatally exposed to HIV underwent evaluation of growth, nutritional, and functional status parameters as part of a prospective study of HIV and nutrition in children...
متن کاملThe challenges of managing antiretroviral treatment in children perinatally infected with HIV in Romania
In the past few years, the rate of HIV perinatally exposed children has increased as a consequence of the expanding number of infected women. These women belong, on the one hand, to Romania’s 1990s cohort, and on the other to the group of new sexually or intravenously (i.v.) drug infected women. To report the characteristics of vertically HIV infected children in the last six years in Romania, ...
متن کامل